Bee Venom

Bee venom is another of Nature’s wonders, perfectly adapted/made for its functions: to defend the bee and its colony.

          However, the active compounds present in bee venom, in small amounts (equivalent of less than 10-30 bee stings per adult) can be very beneficial to human health, if administered by specialized people, in an individualized manner.

“scientific” facts:

Besides water (65-70%), bee venom is a combination of many useful components.

Modem biochemical analytical procedures have been used to identify 18 different components. The major components of bee venom include the following:

PEPTIDES:

  • melittin (family)
  • melittin F
  • apamin
  • mast-cell degranulation peptide 401 (MCD)
  • secarpin
  • tertiapin
  • adolapin
  • protease inhibitor
  • procamine A, B
  • minimine
  • cardiopep

ENZYMES:

  • phospholipase A2
  • hyaluronidase
  • acid phosphomonoesterase [1]
  • glucosidase
  • lysophospholipase

ACTIVE AMINES:

  • histamine
  • dopamine
  • norepinephrine
  • leukotriens

NON-PEPTIDE COMPONENTS

  • carbohydrates
  • Glucose
  • Fructose

LIPIDS

  • 6 phospholipids

AMINO-ACIDS

  • r-aminobutyric acid
  • B-aminoisobutyric acid

          A mature bee “guard” or forager contains in her bee venom sack about 100-150 µg of venom (Schumacher et al., 1989), and young queens about 700 µg (Schmidt, unpublished).

Bee venom can be found under two major forms:

  1. liquid, as it is immediately after extraction or when it is injected by the bee through her stinger; “Bee venom is a colourless, sharp-bitter tasting liquid with an aromatic odour that is similar to ripe bananas. It is slightly acidic 
  2. dried, after collection with special devices (bee venom collectors). The pure whole dried venom has a yellowish brown colour.